gastric ulcers — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4981	Anisotropine Methylbromide		Prostaglandin Receptor , AChR
	Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.		Prostaglandin Receptor , AChR
T1756L	Ilaprazole	IY81149,IY 81149,IY-81149	Proton pump , TOPK
	Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm...		Proton pump , TOPK
T14975	CJ-42794	CJ-042794	Others
	CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-...		Others
T1756	Ilaprazole sodium	IY-81149 sodium	Proton pump , TOPK
	Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus...		Proton pump , TOPK
T14546	Bermoprofen	AD-1590,AJ-1590	Others
	Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.		Others
T68100	Mifentidine	DA 4577	Histamine Receptor
	Mifentidine (DA 4577) is an orally available H2 receptor antagonist for the study of gastric emptying and experimental gastric and duodenal ulcers.		Histamine Receptor
T28136	NC-1300-B	NC1300B,NC 1300 B	ATPase
	NC-1300-B inhibits H(+)-K(+)-ATPase and is used in the study of gastric ulcers.		ATPase
T15687	Thioflosulide	L-745337	COX
	Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.		COX
T19826	Rabeprazole	LY307640	Potassium Channel , STAT
	Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells by targeting STAT3-mediated glycolysis and can be used in the study of gastric ulcers.		Potassium Channel , STAT
T13145	Thiazolidinone-Derivatives-1		Others
	Thiazolidinone-Derivatives-1 inhibits the secretion of gastric acid and can be used in research on the treatment of gastric and duodenal ulcers.		Others
T7099	Gefarnate		Others
	Gefarnate is a synthetic compound used for the treatment of gastric ulcers,and also used in the treatment of dry eye syndrome.		Others
T33846	Oxyphenonium bromide	Spasmophen,Oxifenon,Oxyfenon,Atrenyl,Oxyphenon	Others
	Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms.		Others
T3610	Ranitidine	HSDB 3925,Ranitidin	P450 , Antibacterial , Histamine Receptor
	Ranitidine (HSDB 3925) is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers.		P450 , Antibacterial , Histamine Receptor
TN2078	Pinocembrin chalcone	2',4',6'-Trihydroxychalcone,Pinocembrinchalcone	Calcium Channel , Tyrosinase , Antibacterial , Antifection
	Pinocembrin chalcone is an inhibitor of tyrosinase with antimutagenic effects. Pinocembrin chalcone can be used in studies about the prevention of gastric ulcers.		Calcium Channel , Tyrosinase , Antibacterial , Antifection
T0674	Lansoprazole	A-65006,AG-1749	Proton pump , Phospholipase , Antibacterial
	Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo...		Proton pump , Phospholipase , Antibacterial
T1052	Proglumide		cholecystokinin
	Proglumide (Binoside) is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is...		cholecystokinin
T1651	Rabeprazole sodium	Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium	Apoptosis , Proton pump
	Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. The drug inhibits H(+)-K(+)-exch...		Apoptosis , Proton pump
T10221	Abeprazan hydrochloride	DWP14012 hydrochloride,Fexuprazan hydrochloride	Proton pump
	Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat...		Proton pump
T77599	Methyl retinoate	Retinoic acid, methyl ester	Others
	Methyl retinoate (Retinoic acid, methyl ester) induces aseptic inflammation at the site of administration in in vivo experiments, which causes an increase in the number of leukocytes in the blood and a decrease in the le...		Others
T26090	Rioprostil	TR 4698,TR4698,Rioprostilum,TR-4698
	Rioprostil is a methyl prostaglandin E1 analog that decreases gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the treatment of gastric ulcers and gives significant protection...